Rat Leptin ELISA

Leptin, also known as the hormone of energy expenditure, is created by adipose cells hormone, which assists controlling energy balance via restricting hunger. Leptin is rivalling with the hunger hormone called ghrelin but both hormones perform on receptors in the arcuate nucleus of the hypothalamus, the portion of the brain consisting of a small proportion of nuclei with a wide range of functions. By performing on the hypothalamus to control appetite to achieve energy homeostasis.



Mice with lack of leptin show serious insulin resistance, obesity and decreased fertillity, entire of which are changeable by control of exogenous leptin. In opposition, raised circulating levels of leptin are connected with increased obesity, indicative of an acclimated state of leptin resistance, which is not very good accepted.

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