The Rats of Alpha Centauri





 

 

Interleukin 3

Interleukin 3 (IL-3) is a pleiotropic cytokine, produced mostly by activated T-cells, which can boost the body's natural response to disease as part of the immune system by connecting to the Interleukin 3 Receptor (IL-3R). Interleukin 3 also arouses proliferation, differentiation and survival of haematopoietic cell lines in cells like the granulocytes, monocytes and dendritic, in combination with additional cytokines like Erythropoietin (EPO), Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) and IL-6. It is produced by basophils and activated T-cells to help growth and differentiation of T-cells from the bone marrow in an immunity answer. Activated T-cells, on the other hand, can activate their own proliferation and differentiation or that of other T-cells, which both should participate in connection to IL-2 Receptor (IL-2R) on T-cells.

Rat Interleukin 3 (IL-3), also called multi CSF, is a 26 kDa, occasionally glycosylated monomeric polypeptide. The Rat molecule has two different splice models. The main, Interleukin 3 beta; (IL-3β) is combined as a 169 amino acid forerunner. The second, Interleukin 3 alpha (IL-3α), is identical to the first one, but lacks 3 amino acids.



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