The Rats of Alpha Centauri





 

 

 Interleukin 1β

Interleukin 1 (IL-1) is a name that designates two proteins, IL-1α and IL-1β, that are the products of distinct genes, but recognize the same cell surface receptors. IL-1α and IL-1β are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthezied as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa. The specific protease responsible for the processing of IL-1β, designated interleukin 1β-converting enzyme (ICE), has been described.
Interleukin 1β(IL-1β), produced in Escherichia coli, is a non-glycosylated polypeptide chain containing 152 amino acids and having a molecular mass of 17,400 Da.

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